Antisynthetase-like dermatomyositis related to anti-pm/scl-75: Case report

Main Article Content

Mateus Latrônico Baena
Fabíola Pabst Brener
Henrique Muraoka
Nelzi Queiroz Junior
Lais Zanlorenzi
Patricia Martin
Joao Felipe Bernardi Lora

Keywords

dermatomyositis, myopathy, antisynthetase

Abstract

This article reports the case of a 29-year-old female patient who presented with a severe inflammatory myopathy related to anti-PM/ SCL75 antibodies, with an antisynthetase-like clinical presentation

Abstract 405 | PDF (Español (España)) Downloads 142

References

1. Dahal K, Chaudhary A, Rawal L, Ray U, Paudel S, Khanal P et al. Antisynthetase syndrome and interstitial lung disease: A case report. Ann Med Surg. 2022;82:104571. doi: 10.1016/j.amsu.2022.104571. DOI: https://doi.org/10.1016/j.amsu.2022.104571

2. Karanfilovski V, Janev OG, Nanovic Z, Krstikj LD. Antisynthetase syndrome: A rare and challenging diagnosis – Case report and literature review. Rheumatology. 2022;XXX(3):73-80. doi: 10.35465/30.3.2022.pp73-80. DOI: https://doi.org/10.35465/30.3.2022.pp73-80

3. Moreira C, Shinjo SK. Livro da Sociedade Brasileira de Reumatologia. 3rd ed. São Paulo: Manole; 2023. Avaiable in: vbk://97885204645572023.

4. Lundberg IE, de Visser M, Werth VP. Classification of myositis. Nat Rev Rheumatol. 2018;14(5):269-278. doi: 10.1038/nrrheum.2018.41. DOI: https://doi.org/10.1038/nrrheum.2018.41

5. Korsten P, Rademacher JG, Riedel L, Schnitzler EM, Olgemöller U, Seitz CS, Schmidt J, Larsen J, Vasko R. Antisynthetase Syndrome-Associated Interstitial Lung Disease: Monitoring of Immunosuppressive Treatment Effects by Chest Computed Tomography. Front Med (Lausanne). 2021 Jan 25;7:609595. doi: 10.3389/fmed.2020.609595. DOI: https://doi.org/10.3389/fmed.2020.609595

6. De Lorenzo R, Pinal-Fernandez I, Huang W, Albayda J, Tiniakou E, Johnson C, Milisenda JC, Casal-Dominguez M, Corse AM, Danoff SK, Christopher-Stine L, Paik JJ, Mammen AL. Muscular and extramuscular clinical features of patients with anti-PM/Scl autoantibodies. Neurology. 2018 Jun 5;90(23):e2068-e2076. doi: 10.1212/WNL.0000000000005638. DOI: https://doi.org/10.1212/WNL.0000000000005638

7. Lega JC, Cottin V, Fabien N, Thivolet-Béjui F, Cordier JF. Interstitial lung disease associated with anti-PM/Scl or anti-aminoacyl-tRNA synthetase autoantibodies: a similar condition? J Rheumatol. 2010 May;37(5):1000-9. doi: 10.3899/jrheum.090652. DOI: https://doi.org/10.3899/jrheum.090652